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Paper-Based Microfluidics vs Lateral Flow Assay For Chronic Kidney Disease
M. Mah , S. Cao, S. Konduru
Dr. A. Bellofiore
Technical Advisor:
This study explores two types of point-of-care (PoC)
devices—lateral flow assays (LFAs) and paper-based microfluidics (mPADs)—to determine which can process creatinine more efficiently.
Based on existing research, mPADs are expected to
outperform LFAs in detecting creatinine due to
improved colorimetric response.
To evaluate this, we will: Fabricate and test both device types using
creatinine serums with known concentrations. Image diagnostic pads with an iPhone. Analyze RGB values using ImageJ to quantify color
intensity over time.
Lower RGB values indicate darker coloration and
suggest higher processing efficiency for creatinine
detection.
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