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The integration of UltraViolet-C Light Technology and ATP Biosensors for Real-Time Sterilization and Detection

Sean Nguyen - Biomedical Engineering Department, SJSU;
Alexander Peng - Biomedical Engineering Department, SJSU;
Ryan Vo - Biomedical Engineering Department, SJSU;
Shruthi Srinivasan - Biomedical Engineering Department;

Dr. Yun Wang

Technical Advisor:

Airborne pathogens in healthcare settings can exhibit varying levels of lethality, with mortality rates ranging from 5% to as high as 70% for pathogens such as Tuberculosis, Staphylococcus aureus (MRSA), and Escherichia coli (E. coli). While there are methods that efficiently eliminate airborne pathogens in a room-sized chamber, there isn't a single device that can both eradicate and provide real-time viability of airborne pathogens. This research delves into the measures to combat airborne pathogens, especially in healthcare facilities by adapting Ultraviolet-C light (UV-C) technology. By integrating advanced filtration techniques with powerful real-time detection capabilities, such as ATP biosensors, our aim is to gain insights into the analytics of the presence and activity of pathogens—both live and deceased—to facilitate the quantification of room cleanliness. Our novel approach presents a great potential for transforming infection control practices across settings such as hospitals, labs, and public areas by offering a precise and effective approach to pathogen elimination and enhancing overall air quality. Further studies validating its performance under conditions are essential to optimize its impact on health and safety.

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